What is Pregnancy Vaccine?
Pregnancy vaccine is one of most recent technologies in in vitro fertilization and it facilitates adaptation of the womb to the pregnancy. This procedure somewhat vitalizes and prepares the womb for pregnancy before embryo transfer. Thus, implantability of the embryo is increased.
Who are correct candidates of Pregnancy Vaccine?
- Women who are older than 37 and desire to get pregnant
- Patients with polycystic ovary syndrome
- Patients with chocolate cyst (endometriosis)
- Patients with poor blood circulation in endometrium and coagulation problems
- Patients who could not achieve pregnancy in spite of 2 or more embryo transfers
- Patients with history of recurrent miscarriages
For women meeting above mentioned criteria, pregnancy vaccine helps to increase the chance of pregnancy.
How is Pregnancy Vaccine administered?
Pregnancy vaccine procedure follows following steps;
- First, endometrium, the innermost layer of the womb, is evaluated and various tests are used to determine if there is any pregnancy-related problem.
- Under normal circumstances, in vitro fertilization is started after menstruation. After pregnancy vaccine is decided, blood is also drawn on the day of oocyte pick-up, which is a stage of in vitro fertilization therapy.
- Blood is treated with special processes in laboratory. Meanwhile, a special type of blood cell, called monocyte, is collected and proliferated in culture medium.
- Corticotropin-releasing hormone (CRH) secreted from the brain is also added to the formed culture environment. Thus, production of hormones that boosts implantability of the embryo into endometrium is triggered by stimulating the cells that develop with the help of this hormone.
- Fluids that contain the obtained hormones in culture environment are administered into the uterus before embryo transfer and endomentrium is made eligible for embryo transfer.
Studies demonstrate that pregnancy vaccine increased the rate of conception by 40% in quality embryo transfers, which had to be repeated in the past, and that it decreased rate of misconception following IVF by 30 percent.
However, it is necessary to remember that pregnancy vaccine is not a miracle. It should be considered only for selected cases in order to get maximum success.