Prof. Dr. Engin TUTAR

Undergraduate: Istanbul University Istanbul Faculty of Medicine

Specialization: Dr. Lütfi Kırdar Kartal Training and Research Hospital

Subspecialty: Marmara University Faculty of Medicine

INSTITUTIONS WHERE EDUCATION WAS RECEIVED AND WORKED

• Dr. Lütfi Kırdar Kartal Training and Research Hospital
• Denizli State Hospital
• Denizli SSK Hospital
• Marmara University Faculty of Medicine Hospital
• Ankara Dışkapı Children’s Hospital
• Marmara University Pendik Training and Research Hospital

Specialist in Pediatrics, Subspecialist in Pediatric Gastroenterology, Hepatology, and Nutrition

• Turkish Society of Pediatric Gastroenterology, Hepatology, and Nutrition
• Turkish Pediatric Society
• Marmara Pediatric Association
• Turkish Liver Diseases Society
• Inflammatory Bowel Diseases Society

1. A) International articles
2. Kansu A, Kuloglu Z, Tümgör G, Taşkın DG, Dalgıç B, Çaltepe G, Demirören K, Doğan G, Tuna Kırsaçlıoğlu C, Arslan D, Işık İA, Demir H, Bekem Ö, Şahin Y, Bayrak NA, Selimoğlu MA, Yavuz S, Taşkaya İE, Altay D; VICTORIA Study Group. The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study. Front Pediatr. 2023 Sep 25;11:1272177. doi: 10.3389/fped.2023.1272177. PMID: 37818166; PMCID: PMC10560724.
3. Yilmaz Y, Zeybel M, Adali G, Cosar AM, Sertesen E, Gokcan H, Bahcecioglu HI, Sahin M, Tulunay C, Ergun I, Turan I, Idilman IS, Celikel C, Kirimlioglu H, Akyol G, Yilmaz F, Sokmensuer C, Guveli H, Akarca US, Akyuz U, Genc V, Akyildiz M, Yazihan N, Tutar E, Ates F, Dincer D, Balaban Y, Kiyici M, Akdogan M, Sonsuz A, Idilman R; Members of Fatty Liver Special Interest Group; Yapali S, Dursun H, Aladag M, Satman I, Karcaaltincaba M, Arikan C, Gulerman F, Selimoglu A, Ozen H, Basaranoglu M, Karakan T, Yurci A, Demir K, Koruk M, Uygun A, Sezgin O, Gulec S, Besisik F, Simsek H, Hulagu S, Tozun N, Mardinoglu A, Demir M, Doganay L, Akarsu M, Karasu Z, Kaymakoglu S, Gunsar F. TASL Practice Guidance on the Clinical Assessment and Management of Patients with Nonalcoholic Fatty Liver Disease. Hepatol Forum. 2023 Mar 15;4(Suppl 1):1-32. doi: 10.14744/hf.2023.2023.0011. PMID: 37920782; PMCID: PMC10588738.
4. Volkan B, Akkelle BŞ, Bayrak NA, Tutar E, Kalaycık Şengül Ö, Polat E, Kutluk G, Ertem D. Long-Term Follow-Up and Outcome of Pediatric Acute Pancreatitis: A Multicenter Study. Turk Arch Pediatr. 2023 Jul;58(4):388-394. doi: 10.5152/TurkArchPediatr.2023.22261.
5. Ergenc Z, Kepenekli E, Yakut N, Yapici O, Batu U, Tutar E. Successful Treatment of Fasciola hepatica with Metronidazole in a Child: A Case Report. Iran J Parasitol: Vol. 17, No. 4, Oct-Dec 2022, pp.596-598.
6. Méndez-Sánchez N, Bugianesi E, Gish RG, Lammert F, Tilg H, Nguyen MH, Sarin SK, Fabrellas N, Zelber-Sagi S, Fan JG, Shiha G, Targher G, Zheng MH, Chan WK, Vinker S, Kawaguchi T, Castera L, Yilmaz Y, Korenjak M, Spearman CW, Ungan M, Palmer M, El-Shabrawi M, Gruss HJ, Dufour JF, Dhawan A, Wedemeyer H, George J, Valenti L, Fouad Y, Romero-Gomez M, Eslam M; Global multi-stakeholder consensus on the redefinition of fatty liver disease. Global multi-stakeholder endorsement of the MAFLD definition. Lancet Gastroenterol Hepatol. 2022 May;7(5):388-390.doi: 10.1016/S2468-1253(22)00062-0. Epub 2022 Mar 3. PMID: 35248211.
7. Umay E, Eyigor S, Giray E, Karadag Saygi E, Karadag B, Durmus Kocaaslan N, Yuksel D, Demir AM, Tutar E, Tikiz C, Gurcay E, Unlu Z, Celik P, Unlu Akyuz E, Mengu G, Bengisu S, Alicura S, Unver N, Yekteusaklari N, Uz C, Cikili Uytun M, Bagcier F, Tarihci E, Akaltun MS, Ayranci Sucakli I, Cankurtaran D, Aykın Z, Aydın R, Nazli F. Pediatric dysphagia overview: best practice recommendation study by multidisciplinary experts. World J Pediatr. 2022 Jul 11. doi: 10.1007/s12519-022-00584-8. Online ahead of print.
8. Akkelle BS, Ertem D, Volkan B, Tutar E. Phenotypic pattern of early versus later-onset pediatric inflammatory bowel disease in a eurasian country. J Pediatr Gastroenterol Nutr. 2022 Oct 1;75(4):e61-e66. doi: 10.1097/MPG.0000000000003557. Epub 2022 Sep 20.
9. Akkelle BS, Sengul OK, Tutar E, Volkan B, Celikel CA, Ertem D. Low titer tissue transglutaminase antibodies: a link to H. pylori infection? Dig Dis 2022; 40(2):168-174. doi: 10.1159/000516479. Epub 2021 Apr 23.
10. Sengul OK, Akkelle BS, Ay P, Volkan B, Tutar E, Celikel CA, Ertem D. Evaluation of mucosal status in the follow-up of pediatric patients with celiac disease: the role of serology. Eur J Pediatr. 2022 Sep;181(9):3283-3289. doi: 10.1007/s00431-022-04535-3. Epub 2022 Jun 23.
11. Akkelle BS, Volkan B, Tutar E, Ertem D. Characteristics of Siblings With Celiac Disease Diagnosed by Family Screening. Indian Pediatr. 2022 Sep 22;S097475591600458. Online ahead of print.
12. Urgancı N, Ozgenc F, Kuloğlu Z, Yüksekkaya H, Sarı S, Erkan T, Önal Z, Çaltepe G, Akçam M, Arslan D, Arslan N, Artan R, Aydoğan A, Balamtekin N, Baran M, Baysoy G, Çakır M, Dalgıç B, Doğan Y, Durmaz Ö, Ecevıt Ç, Eren M, Gökçe S, Gülerman F, Gürakan F, Hızlı S, Işık I, Kalaycı AG, Kansu A, Kutlu T, Karabiber H, Kasırga E, Kutluk G, Hoşnut FÖ, Özen H, Özkan T, Öztürk Y, Soylu ÖB, Tutar E, Tümgör G, Ünal F, Ugraş M, Üstündağ G, Yaman A, Turkish Ibd Study Group. Familial Mediterranean Fever Mutation Analysis in Pediatric Patients With İnflammatory Bowel Disease: A Multicenter Study. Turk J Gastroenterol. 2021; 32(3):248-250. doi: 10.5152/tjg.2021.20057
13. Akkelle BS, Sengul OK, Volkan B, Tutar E, Ergelen R, Yardimci S, Ertem D. Outcomes of Pediatric Fistulising Perianal Crohn’s Disease. Turk J Gastroenterol. 2021; 32(3):240-247. doi: 10.5152/tjg.2021.191034.
14. Ozen A, Kasap N, Vujkovic-Cvijin I, Apps R, Cheung F, Karakoc-Aydiner E, Akkelle B, Sari S, Tutar E, Ozcay F, Kocacik Uygun D, Islek A, Akgun G, Selcuk M, Balci Sezer O, Zhang Y,Kutluk G, Topal E, Sayar E, Celikel C, Houwen RHJ, Bingol, Ogulur I, Bilgic Eltan S, Snow AL, Lake C, Fantoni G, Alba C, Sellers B, Chauvin SD, Dalgard CL, Harari O, Ni YG, Wang MD, Devalaraja-Narashimha K, Subramanian P, Ergelen R, Artan A, Guner SN, Dalgic B, Tsang J, Belkaid Y, Ertem D, Baris S, Lenardo MJ. Broadly effective metabolic and immune recovery with C5 inhibition in CHAPLE disease. Nat Immunol. 2021 Feb;22(2):128-139. doi: 10.1038/s41590-020-00830-z.
15. Cetiner N, Saylan Cevik B, Tutar E, Erolu E, Ak K, Akalın F. Constrictive pericarditis diagnosed following liver transplantation. Marmara Med J 2021;34(3): 335-338. Doi: 10.5472/marumj.1012634
16. Polat E, Bayrak NA, Tutar E, Celikel C, Tokuc G, Ertem D. Colorectal Carcinoma in Childhood. JPGN Reports. 2021; 2:1(e039). DOI: 10.1097/PG9.0000000000000039
17. Kesim S, Turoglu HT, Tutar E, Ozguven S, Erdil TY. 99mTc-MDP Bone Scintigraphy in Gaucher Disease. Clin Nucl Med. 2020 Oct;45(10):e455-e456.doi: 10.1097/RLU.0000000000003140.
18. Bayrak NA, Tutar E, Volkan B, Akkelle BS, Polat E, Kutluk G, Ertem D. Helicobacter pylori infection in children with celiac disease: Multi-center, cross-sectional study. Helicobacter 2020 Jun; 25(3):e12691. doi: 10.1111/hel.12691.
19. Akkelle BŞ, Tutar E, Ergelen R, Çelikel Ç, Ertem D. IgG4 related disease in a 7 year old girl with multiple organ involvement: A rare presentation. Turk Pediatri Ars 2020; 55(2): 191–4. DOI: 10.14744/TurkPediatriArs.2019.83435
20. Kalaycık Şengül Ö, Volkan B, Tutar E, Çelikel Ç, Ertem D. Gastrointestinal sarcoidosis presenting with malabsorbtion at an early age. Turk Pediatri Ars 2020; 55(4): 441-4. DOI: 10.14744/TurkPediatriArs.2019.93274
21. Tutar E, Bayrak NA, Volkan B, Ertem D. Bowel Preparation for Colonoscopy in Children: 1 Day PEG-3350 with Bisacodyl versus 3 Day Sennosides. Dig Dis. 2019; 37(4):334-342. DOI: 10.1159/000497819
22. Akkelle BS, Tutar E, Volkan B, Sengul OK, Ozen A, Celikel CA, Ertem D. Gastrointestinal Manifestations in Children with Primary Immunodeficiencies: Single Center: 12 Years Experience. Dig Dis. 2019; 37 (1):45-52. doi: 10.1159/000492569.
23. Polat E, Thomas G, Tutar E, Türkdoğan D, Ekinci G, Ertem D. Neurologic Wilson Disease Presenting with Acute Delirium And Automatic Writing Behaviour: A Case Report. Journal of Biology Engineering and Medicine. 2019; 1(1):1-4. doi:10.31487/j.JBEM.2019.01.01
24. Ozturk Thomas G, Tutar E, Tokuc G, Oktem S. 25-hydroxy Vitamin D Levels in Pediatric Asthma Patients and its Link with Asthma Severity. Cureus. 2019 Mar 22; 11(3):e4302. DOI: 10.7759/cureus.4302
25. Akkelle BS, Tutar E, Sengul OK, Celikel CA, Ertem D. A Rare Complication of Giardiasis in Children: Protein Losing Enteropathy. The Pediatric Infectious Disease Journal 2018 Dec; 37(12):e345-e347. doi: 10.1097/INF.0000000000002025.
26. Ozen A, Comrie WA, Ardy RC, Conde CD, Dalgic B, Beser OF, Morawski AR, Karakoc Aydiner E, Tutar E, Baris S, Ozcay F, Serwas NK, Zhang Y, Matthews HF, Pittaluga S, Folio LR, Aksu AU, McElwee JJ, Krolo A, Kiykim A, Baris Z, Gulsan M, Ogulur I, Snapper SB, Houwen RHJ, Leavis HL, Ertem D, Kain R, Sari S, Erkan T, Su HC, Boztug K, and Lenardo MJ. CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis. N Engl J Med. 2017 Jul 6;377(1):52-61 doi: 10.1056/NEJMoa1615887.
27. Uygur P, Oktem S, Boran P, Tutar E, Tokuc G. Low vs. high flow oxygen delivery systems in children with lower respiratory infection. Pediatr Int. 2016 Jan; 58(1): 49-52. doi: 10.1111/ped.12750.
28. Aykan M, Aydın S, Öktem S, Demir MG, Tutar E. Effect of adenoid hypertrophy and pulmonary function tests in children with mild asthma. Kulak Burun Bogaz Ihtis Derg. 2016 Sep-Oct;26(5):253-7. doi: 10.5606/kbbihtisas.2016.88725.
29. Kocaaslan ND, Tuncer FB, Tutar E, Celebiler O. Acute liver failure and hepatic encephalopathy after cleft palate repair. Cleft Palate-Craniofacial Journal 2015; Sep 52 (5):629-31.
30. Kutluk G, Tutar E, Bayrak A,Volkan B, Akyon Y, Celikel C, Ertem D. Sequential therapy versus standard triple therapy for Helicobacter pylori eradication in children: any advantage in clarithromycin-resistant strains? Eur J Gastroenterol Hepatol. 2014 Nov;26(11):1202-8. doi: 10.1097/MEG.0000000000000190.
31. Oktem S, Tutar E, Dursun B, Boran P. Treatment in congenital pulmonary airway malformation: A case report and review of the literature. Nobel Medicus, 2013; 9(3):133-5
32. Tutar E, Kutluk G, Bayrak NA, Çelikel Ataizi Ç, Pehlivanoğlu E, Ertem D. What is the diagnostic utility of endoscopic scoring systems in children? Turk J Gastroenterol 2013; 24 (1):22-9. doi: 10.4318/tjg.2013.0700
33. Karakaş A, Tutar E, Tokuç G, Öktem S, Boran P. Hepatosplenic Candidiasis with Generalized Cutaneous Nodular Lesions: A Case Report. J Pediatr Inf 2013; 7: 39-42. doi:10.5152/ced.2013.09
34. Tutar E, Boran P, Öktem S, Tokuç G, Çalışkan B. Malnutrition in hospitalized pediatric patients: a comparison of the National Turkish and World Health Organization (WHO) child growth standards. Marmara Med J, 2012; 25(3): 128-132, doi: 10.5472/MMJ.2012.02242.1
35. Tutar E, Tokuç G, Özcabı B, Boran P. A nine-year-old boy with double vision, speech disturbance, fatigue and strength loss of extremities. Turk Arch Ped, 2009; 44(4): 149-51.
36. Tutar E, Cihan MK, Uysal G, Sayli T. Epstein-Barr virus-induced severe hepatitis in an immunocompetent infant. Turk J Gastroenterol, 2009; 20(2):154-5.
37. Tutar E, Ertem D, Karaa E, Pehlivanoglu E. Endoscopic and histopathologic findings associated with H.pylori infection in very young children. Dig Dis Sci, 2009; 54(1):111-7.
38. Tutar E, Ertem D, Unluguzel G, Tanrikulu S, Haklar G, Celikel C, Ademoglu E, Pehlivanoglu E. Reactive oxygen species and chemokines: Are they elevated in the esophageal mucosa of children with gastroesophegeal reflux disease? World J Gastroenterol, 2008; 14(20):3218-23.
39. Ertem D, Tutar E, Cam S, Ugras M, Pehlivanoglu E. Severe gastric outlet obstruction in a child with ectopic pancreas: is there a role for Helicobacter pylori? J Pediatr Gastroenterol Nutr, 2006; 43(3):385-7.
40. Ugras M, Ertem D, Cam S, Tutar E, Pehlivanoglu E. Can gastro-oesophageal reflux be predicted while advancing the endoscope through the laryngeal area? Gut, 2005; 54(6);890
41. B) National articles, reviews, and book chapters
42. Akkelle BŞ, Volkan B, Dursun C, Korkmaz B, Karaoğlu S, Tutar E, Ertem D. Evaluation of endoscopic findings in children presenting due to corrosive-caustic substance exposure: Retrospective study. Turkiye Klinikleri J Med Sci. 2023; 43(1):22-8.
43. Bayrak NA, Tutar E. Invasive and non-invasive tests used in the diagnosis of Helicobacter pylori infection in children. Ertem D, Tutar E, editors. Helicobacter pylori Infection in Childhood: A Comprehensive Overview. 1st Edition. Ankara: Türkiye Klinikleri; 2023. p.28-33.
44. Akkelle BS, Tutar E. Nutrition and Gastroesophageal Reflux Disease in Children with Neuromuscular Disease. In: Respiratory Monitoring in Children with Neuromuscular Disease. Karakoç F, Gökdemir Y (ed). Özel Ofset Basın Yayın Matbaa Reklam İnş. Turz. Tic. San. Ltd. Şti., Ankara, 2022; 69-82. ISBN: 978-625-00-9382-5, Certificate No: 40365.
45. Akkelle BS, Tutar E. Evaluation of diagnostic factors in pediatric celiac disease: Descriptive retrospective study. Turkiye Klinikleri J Pediatr. 2022; 31(3):179-84.
46. Akkelle BŞ, Tutar E, Ertem D. Factors affecting adherence to gluten-free diet treatment in pediatric celiac disease. Nutrition and Dietetics Journal 2022; 50(2):48-55.
47. Akkelle BS, Tutar E. Physiology and functions of the pancreas. In: Pediatric Department of İzmir Dr. Behçet Uz Children’s Hospital. Özkan B (ed). Ankara Nobel Medical Bookstore Ltd. Co., Ankara, 2022; 885-887. ISBN: 978-625-7546-55-7, Certificate No: 49889.
48. Tutar E. Gastrointestinal System Bleeding. In: Pediatrics 3rd Edition. Yakıncı C, Topal E (eds). İnönü University Publishing, Malatya, February 2021; 241-249. ISBN 978-605-7853-61-5, Certificate No: 49391
49. Tutar E. Functional Foods: Honey and Mushrooms. In: Functional Foods. Baysoy G (ed). Ankara Nobel Medical Bookstore Ltd. Co., Ankara, April 2018; 297-318
50. Tutar E. Congenital Diarrhea: Transport Disorders. In: Pediatric Chronic Diarrhea. Kansu A, Arıkan Ç (ed). HTC Offset Printing Publishing Trade Ltd. Co., Ankara, 2015; pp:161-170
51. Tutar E, Ertem D. In the book: Pediatric Chest Diseases with Cases. Karakoç F, Çakır E, Öktem S (ed). Nobel Medical Bookstore Trade Ltd. Sti, Istanbul, October 2014.

– 18. Case: A nine-year-old asthmatic patient with complaints of chest pain and bitter water coming into the mouth, pp:79-85, 37. Case: A two-year-old cystic fibrosis patient with growth retardation and elevated liver function tests, pp: 163-167, 70. Case: A twelve-year-old patient diagnosed with cerebral palsy presenting with fever, weakness, and shortness of breath, pp: 301-304

11. Yılmaz EK, Him NB, Kepenekli E, Volkan B, Tutar E, Koç A, Çelikel Ç, Soysal A. Visceral Leishmaniasis in non-endemic areas: Case presentation. Journal of Pediatric Specialty Academy, 2013; 1:29-31.
12. Tutar E. Honey and Mushrooms. In: Functional Foods. Baysoy G (ed). Akademi International Publishing Industry and Trade Ltd. Co., Istanbul, 2013; 190-200.
13. Tutar E, Karakaş A, Boran P, Berk B, Güven SB. Donohue Syndrome (Leprechaunism): Case Presentation. Children’s Journal 2012; 12(4):189-192, doi:10.5222/j.child.2012.189
14. Deniz C, Öktem S, Şimşek Ş, Tutar E, Tokuç G. Prevalence of M. pneumoniae and C. pneumoniae in wheezing children. Children’s Journal, 2012; 12(1): 30-34, doi:10.5222/j.child.2012.030
15. Boran P, Tokuç G, Yardımcı E, Büyükkalfa D, Tutar E, Yazıcı N. Evaluation of children with idiopathic thrombocytopenic purpura. Children’s Journal, 2009; 9(4):181-5.
16. Tutar E, Ertem D. Gastrointestinal Bleeding. In: Pediatric Intensive Care: Principles and Practices. Karaböcüoğlu M, Köroğlu TF (eds). Istanbul Medical Publishing, Istanbul, 2008; 699-718.
17. Ağzıkuru S, Tokuç G, Öktem S, Tutar E. Retrospective examination of cases presenting with arthritis findings. Zeynep Kamil Medical Bulletin, 2004; 35:23-7.
18. Öktem S, Deniz C, Tokuç G, Tutar E, Ağzıkuru S, Boran P. Evaluation of our cases with tuberculosis meningitis. Zeynep Kamil Medical Bulletin, 2004; 35(4):205-9.
19. Öktem S, Tokuç G, Yıldırım T, Tutar E, Ağzıkuru SB. Evaluation of children with pneumonia treated in our clinic. Zeynep Kamil Medical Bulletin, 2004; 35(4):211-214.
20. Narter F, Ketenci Ö, Tokuç G, Tutar E, Öktem S. Hypercalcemia in distal renal tubular acidosis. Istanbul Medical Faculty Children’s Journal, 2003; 3:72-4.
21. Bostan Ö, Öktem S, Tokuç G, Narter F, Tutar E, Girit N, Esmer K. Sociodemographic characteristics of hospitalized patients in our Children’s Clinic. Kartal Training and Research Hospital Medical Journal, 2003; 14:11-4.
22. Uzer A, Tutar E, Tokuç G, Öktem S. Imaging in urinary system infections. Kartal Training and Research Hospital Medical Journal, 2002; 13:182-5.
23. Tutar E, Tokuç G, Boylu S, Şan E, Vitrinel A, Öktem S, Girit N, Narter F, Kargı B. Retrospective evaluation of 40 cases with parapneumonic effusion and empyema. Children’s Journal, 2002; 2:264-8.
24. Tutar E, Temel F, Tokuç G, Şan E, Vitrinel A. Examination of insulin-dependent diabetes and diabetic ketoacidosis through our cases. Kartal Training and Research Hospital Medical Journal, 2000; 11:814-6.
25. Tutar E, Tokuç G, Öktem S. Antithrombin III levels and their relationship with idiopathic respiratory distress syndrome in healthy and sick newborns. Kartal Training and Research Hospital Medical Journal, 2000; 11:870-3.
26. Sancar A, Tokuç G, Öztürk M, Tutar E, Özgüner A. The role of serum albumin-prealbumin values and anthropometric measurements in the nutritional follow-up of newborns. Kartal Training and Research Hospital Medical Journal, 1992; 3:267-9.
27. Özgüner A, İnalhan M, Tutar E, Oran O. Multicystic dysplastic kidney disease (a case presentation). Kartal Training and Research Hospital Medical Journal, 1990; 1:237-9.
28. Söylemezoğlu O, Tural L, Özgüner A, İnalhan M, Tutar E. Ketotifen prophylaxis in wheezing children. Clinical Research Bulletin, 1990; 8:1-3.
29. Özgüner A, İnalhan M, Oran O, Akgün E, Tutar E. The importance of ultrasonography in the diagnosis and follow-up of pleural effusions. Kartal Training and Research Hospital Medical Journal, 1990; 1:221-2.