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ayla.guven@hisarhospital.com
0216 524 13 00

GÖREV ALDIĞI HASTANELER

  • Hisar Hospital Intercontinental

Prof. Dr. Ayla Güven 1986 yılında Gazi Üniversitesi Tıp Fakülte’sinden mezun olduktan sonra Ege Üniversitesi Göğüs hastalıkları Bornova Verem Savaş Dispanserinde zorunlu hizmetini tamamlamıştır. Takiben Hacettepe Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalında uzmanlık eğitimine başlamış ve 1993 yılında uzman olmuştur. Uzman hekim olarak çalışmayı takiben Gazi Üniversitesi Tıp Fakültesi Çocuk Endokrinolojisi Bilim Dalı’nda Eylül 2000 de yan dal uzmanlık eğitimine başlamış, Aralık 2002 de Çocuk Endokrinolojisi uzmanı olmuştur. Nisan 2003 tarihinde Ondokuz Mayıs Üniversitesi Tıp Fakültesinde yardımcı doçent olarak çalışmaya başlamış, Mayıs-Kasım 2003 tarihleri arasında Amerika Birleşik Devletleri Pittsburgh Çocuk Hastanesi Çocuk Endokrinolojisi  ve Diyabet bölümünde çalışmıştır. Ülkemize döndükten sonra Ondokuz Mayıs Üniversitesi Tıp Fakültesinde çalışmaya devam etmiştir. Bu klinikte ilk kez Çocuk Endokrinolojisi yan dalı verilmeye başlamıştır. Çalıştığı dönemde klinikte çocuk endokrinolojisi uzmanları yetiştirmiştir. 13.03.2006 tarihinde yapılan sınavı başarı ile vererek Doçent ünvanı almıştır. Aralık 2006 tarihinden itibaren Göztepe Eğitim ve Araştırma Hastanesinde çalışmaya başlamıştır. Bu hastanede Kasım 2008 de Çocuk Endokrin klinik şefi  olarak atanmış ve Mart 2009 tarihinden itibaren hastanede ilk defa Çocuk Endokrinolojisi yan dal eğitimi vermeye başlamıştır. 2009-2017 tarihleri arasında Çocuk Endokrinolojisi uzmanları yetiştirmiştir. Yan dal uzmanlık eğitimi verdiği hekimlerin birçoğu profesör ve doçent olarak akademik başarı elde  elde ederek hastalarına hizmet vermeye devam etmektedirler. 2017-2021 tarihleri arasında Sağlık Bilimleri Üniversitesi Zeynep Kamil Çocuk ve kadın hastalıkları hastanesinde eğitim görevlisi olarak çalıştıktan sonra kamu hizmetinden isteği ile emekli olmuştur. 2021-2024 tarihleri arasında Başkent Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve hastalıkları ana bilim dalı kadrosunda İstanbul Hastanesinde Çocuk endokrinolojisi uzmanı olarak çalışmıştır. 2024 itibariyle Hisar Hospital Intercontinental ‘de hizmet vermektedir.

TIBBİ İLGİ ALANLARI

  • Adet bozuklukları ve kızlarda kıllanma artışı, polikistik over sendromu
  • Adrenal hastalıklar
  • Cinsel gelişim bozuklukları
  • Tip2 diyabet
  • Tiroit hastalıkları
  • Büyüme bozuklukları : kısa boyluluk ve uzun boyluluk
  • Ergenlik bozuklukları: erken ergenlik-gecikmiş ergenlik

Lisans: Gazi Üniversitesi  Tıp Fakültesi

Uzmanlık: Hacettepe Üniversitesi Tıp Fakültesi

Yan Dal Uzmanlık: Gazi Üniversitesi Tıp Fakültesi

Yurt Dışı Deneyim:University of Pittsburgh, Department of Pediatrics, Division of Pediatrik Endocrinology

EĞİTİM ALDIĞI ve ÇALIŞTIĞI KURUMLAR

Bilgi eklenecektir.

Endocrine Society

Pediatrik Endokrinoloji ve Oksoloji Derneği, 

Milli Pediatri Derneği

İstanbul Tabip Odası

A1. SCI ( SCIENCE CITATION INDEX ) ve SCI-EXPANDED KAPSAMINDAKİ DERGİLERDE YAYINLANAN MAKALELER

1- Güven A, Baskın D. Lymphomatoid Graulomatosis in a boy with long-term follow-up.  Ped Hematol Oncol 2001;18:377-382.

2-Güven A Hepatitis and hematuria in scarlet fever. Indian J Pediatr 2002; 69:985-986. 

3-Güven A. Amebiasis of the newborn: report of a case. Indian J Pediatr 2003; 70:437-38.

4-Güven A. Intramuscular antibiotic treatment in infants and pre-school children with urinary tract infection.  Indian J Pediatr 2004;71:979-981. 

5-Güven A, P. Cinaz, Bideci A. Is premature adrenarche risk for atherogenesis? Pediatr Int 2005;47:20-25. 

6-Güven A, Aygun C,İnce H,Aydın M, Pınarlı FG, Baysal K, Küçüködük S. Severe Hypothyroidism caused by hepatic hemangioendothelioma in an infant of a diabetic mother. Horm Res 2005;63:86-89. 

7-Cinaz, P,Bideci A,Çamurdan MO, A. Güven A, Gönen S. Leptin and soluble leptin receptor levels in obese children in fasting and satiety states. J Pediatr Endocrinol Metab 2005;18:303-307.

8-Güven A, Cinaz P, Ayvalı E. Are growth factors and leptin involved in the pathogenesis of premature adrenarche in girls? J Pediatr Endocrinol Metab 2005;18:785-791.

9-Güven A, Karadeniz S, Aydin O, Akbalik M, Aydin M. Fatal Disseminated cytomegalovirus infection in an infant with Cushing’s Syndrome caused by topical steroid. Horm Res 2005; 64:35-38.

10-Dursun  H, Cinaz P, Bideci  A, Guven A , Aybay C, Elbeg S. Serum levels of sL-selectin and tumour necrosis factor-α in children with type 1 diabetes mellitus. Acta Diabetol 2007; 44:1–5

11-Güven A, Özgen T, Belet Ü, Aydın M. Acromegaly Symtomps Without Pituitary Adenoma In An Adolescent.  J Pediatr Endocrinol  Metab 2007;20:945-949

12-Güven A, Gülümser Ö, Özgen T. Cushing’s Syndrome And Adrenocortical Insufficiency Caused By Topical Steroids:  Is Misuse Or Abuse?  J Pediatr Endocrinol  Metab 2007;20; 1173-1182

13-Güven A, Kara N, Saglam Y, Guneş S, Okten G. The Mayer-Rokitansky-Kuster-Hauser Syndrome in a girl with 45,X / 46,X, del(X) (p11.21). Am J Med Genet  2008;146:128-131

14-Güven A, Sanisoğlu Y. Pubertal Progression and Serum Lipid Profile in Obese Children. J Pediatr Endocrinol  Metab 2008; 21: 135-137

15-Güven A, Odaci  H, Özgen IT, Bek  Y. The effects of individual factors on adolescent obesity: A study in Turkey. Pediatr Int. 2008;50:356-362

16-Güven A, Mutus M, Bilgic O, Okur H. Complete vaginal agenesis in girl with Mayer- Rokitansky-Kuster-Hauser Syndrome Type II. J Pediatr Endocrinol Metab. 2008;21:409

17-Güven A, Dağçınar A, Ceyhan M. Coexistence of craniovertebral junction stenosis with pancake kidney in an adolescent with acromesomelic dysplasia. J Pediatr Endocrinol Metab. 2008;21:941.

18-Aslan A, Yildirim M, Ayyildiz M, Güven A, Agar E.The role of nitric oxide in the inhibitory effect of ghrelin against penicillin-induced epileptiform activity in rat. Neuropeptides 2009;43:295-302

19-Özgen T, Güven A, Aydın M. Precocious puberty in a girl with Down syndrome due to primary hypothyroidism. Turk J Pediatr. 2009;51:381-383

20-Güven A, Özgen T, Aliyazıcıoglu Y. Adiponectin and resistin concentrations after glucose load in adolescents with polycystic ovary syndrome. Gynecol Endocrinol 2010;23:1-9

21-Aslan A, Yildirim M, Ayyildiz M, Güven A, Agar E. Interaction of leptin and nitric oxide pathway on penicillin-induced epileptiform activity in rats. Brain Res. 2010; 19;1321:117-24.

22-Ozgen IT, Aydin M, Guven A, Aliyazıcıoglu Y. Characteristics of Polycystic Ovarian Syndrome and Relationship with Ghrelin in Adolescents. J Pediatr Adolesc Gynecol. 2010;23:285-289

23-Güven A, Kırmızıbekmez H. Multiple pterygium syndrome: mimicking the findings of Turner Syndrome. J Pediatr Endocrinol Metab 2011;24:1089–1093

24-Dursun F, Güven A, Ayhan Yİ. Kocher Debre Semelaigne Syndrome with pericardial effusion. J Pediatr Endocrinol Metab 2011;24:1099–1101.

25-Cebeci AN, Güven A. Delirium in diabetic ketoacidosis. J Clin Res Pediatr Endocrinol 2012;4:39-41

26-Kırmızıbekmez H, Güven A, Yıldız M, Cebeci N, Dursun  F. Developmental Defects of Thyroid Gland: Relationship with Advanced Maternal Age. J Clin Res Pediatr Endocrinol 2012;4:71-74

27-Dursun F, Güven A, Morris-Rosendahl D. Warburg Micro syndrome. J Pediatr Endocrinol Metab 2012;25: 379-382

28-Gurbuz F, Kotan LD, Mengen E, Sıklar Z, Dökmetas S, Guven A, Kirel B, Saka N, Cesur Y, Özen S, Ozbek MN, Kekil MB, Temiz F, Onenli Mungan N, Yuksel B, Topaloglu AK. Distribution of Gene Mutations Associated with Familial Normosmic Idiopathic Hypogonadotropic Hypogonadism. J Clin Res Pediatr Endocrinol 2012;4:121-126.

29-Cebeci N, Güven A, Kırmızıbekmez H, Yıldız M, Dursun F. Clinical Features and Management of Diabetic ketoacidosis in Different Age Groups of Children: Children Less Than Five Years of Age Are at Higher Risk of Metabolic Decompensation. J Pediatr Endocrinol Metab 2012;25 :917-925

30-Guven A, Cebeci N, Dursun A, Aktekin E, Baumgartner M, Fowler B. Methylmalonic acidemia mimicking diabetic ketoacidosis in an infant. Pediatr Diabetes. 2012 Sep;13:e22-5.

31-Flanagan SE, Xie W, Caswell R, Damhuis A, Vianey-Saban C, Akcay T, Darendeliler F, Bas F, Guven A, Siklar Z, Ocal G, Berberoglu M, Murphy N, O’Sullivan M, Green A, Clayton PE, Banerjee I, Clayton PT, Hussain K, Weedon MN, Ellard S. Next generation sequencing reveals deep intronic cryptic ABCC8 and HADH splicing founder mutations causing hyperinsulinaemic hypoglycaemia by pseudoexon activation. Am J Hum Genet. 2013;92:131-6.

32-Cebeci N, Guven A, Saltık S, Mesci C.Hoffmann’s syndrome and pituitary hyperplasia in an adolescent secondary to Hashimoto thyroiditis. J Pediatr Endocrinol Metab 2013;26:747-51

33-Güven A, Dursun F, Özkanlı S, Güçlüer B, Kuru Lİ. Complete androgen insensitivity syndrome and discordant müllerian remnants: two cases with novel mutation in the androgen receptor. J Pediatr Endocrinol Metab 2013;26:909-914

34-Cebeci AN, Güven A, Yıldız M. Profile of hypothyroidism in Down’s syndrome. J  Clin Res Pediatr Endocrinol. 2013;5:116-20

35-Güven A, Baltacıoğlu F, Dursun F, Cebeci AN, Kırmızıbekmez H. Remission with cabergoline in adolescent boys with Cushing’s disease. J Clin Res Pediatr Endocrinol 2013;5:194-8

36-Danne T, Philotheou A, Goldman D, Guo X, Ping L, Cali A, Johnston P. Katkıda bulunanlar: Mazza C, Ropolo M, Trifone L, Borkenstein M, Schober E, Borges JLC, Forti A, Hissa M, Kupfer R, Pinto M, Tschiedel B, Arriaza M, Muzzo S, Rumie, Ugarte HF, Cervickova B, Lebl J, Roschlova I, Skvor J,  Venhacova J, Kapellen T, Knerr I, Meißner T, Ziegler R, Almássy Z, Barkai L, Blatniczky L, Oroszlan G, Turi S, Dharmalingam M, Jain S, Kalra S, Kumar P, Shamanna P, Barrientos M, Cervera MA, Escalante JM, Mancillas L, Bindels R, J Calderon J, Calderon M, Lu L, Mysliwiec M, Szewczyk L, Witkowski D, Andreica M, Bzduch M, Cret V, Dumbrava L, Fetecau G, Micle I, Mihai C, Mihu M,  Moldovan L, Motoc-Raceala MS, Puiu I, Bashnina E, Malievsky O, Peterkova V, Petryakina E, Tuz V, Pillay K, Segal D, van Dyk J, Gómez A, López MJ, Luzuriaga C, Pombo M, Rodríguez M, BenBecher S, Guediche N, Hachicha M, Sfar T, Guven A, Kandemir N, Appiagyei-Dankah Y, Bernier A, Danney M, Foster M, Franklin S, Kummer M, Maniatis A, Prakasam G, Quattrin T, Reiner B, Ross J, White P, Willi S. A randomized trial comparing the rate of hypoglycemia – assessed using continuous glucose monitoring – in 125 preschool children with type 1 diabetes treated with insulin glargine or NPH insulin (the PRESCHOOL study). Pediatr Diabetes. 2013 Dec;14(8):593-601

37-Güven A, Hancili S. Bilateral Galactocele In A Male Infant With Down Syndrome And Congenital Hypothyroidism. Ped Intern, 2013;55(5):e116-8

38-Kırmızıbekmez H, Güven A, Yıldız M, Dursun F, Cebeci N, Hancili S. Detection of vascular risk markers in children and adolescents with type 1 diabetes. J Pediatr Endocrinol Metab. 2014:27:87-92

39-Güven A, Hancili S, Kuru LI. Obesity and Increasing Rate of Infantile Blount Disease. Clinical Pediatrics, 2014: 53:539-43

40-Güven A, Hancili S, Karatoprak EY, Tasel B. Symptomatic cerebral infarction in a child with severe diabetic ketoacidosis. J Pediatr Endocrinol Metab. 2014; 27:1001-1004

41-Cebeci AN, Güven A. Does maternal obesity have an influence on feding behaviour of obese children. Minerva Pediatr 2015;67:481-487.

42-Danne T, Becker RH, Ping L, Philotheou A, Katkıda bulunanlar: Mazza C, Ropolo M, Trifone L, Borkenstein M, Schober E, Lindolfo J, Borges C, Forti A,  Hissa M, Kupfer R, Pinto M, Balduino T, Arriaza M, Muzzo S, Rumie H, Ugarte F, Cervickova B, Lebl J, Roschlova I, Skvor J, Venhacova  J, Kapellen T,  Knerr I, Meißner T, Ziegler R, Almassy Z, Barkai L, Blatniczky L, Oroszlan G, Turi S, Dharmalingam M, Jain S, Kalra S, Kumar, P Shamanna P, Barrientos M, Cervera MA, Escalante JM, Mancillas L, Bindels R, Calderon J, Calderon M, Lu L, Mysliwiec M, Szewczyk L, Witkowski D, Andreica M, Bzduch M,  Cret V,  Dumbrava L, Fetecau G, Micle I, Mihai C, Mihu M, Moldovan L, Motoc-Raceala MS, Puiu I, Bashnina E, Malievsky O, Peterkova V, Petryakina E, Tuz V, Philothoeu A,  Pillay K, Segal D, van Dyk J, Gomez A, Lopez MJ, Luzuriaga C, Pombo M, Rodríguez M, Becher SB, Guediche N, Hachicha M, Sfar T, Guven A, Kandemir N, Appiagyei-Dankah Y, Bernier A, Danney M, Foster M, Franklin S, Kummer M, Maniatis A, Prakasam G, Quattrin T, Reiner B, Ross J, White P, Willi S. Insulin glargine metabolite 21A-Gly-human insulin (M1) is the principal component circulating in the plasma of young children with type 1 diabetes: results from the PRESCHOOL study. Pediatr Diabetes. 2015;16:299-304, 

43-Güven A, Cebeci AN, Hancili S. Gonadotropin releasing hormone analog treatment in children with congenital adrenal hyperplasia complicated by central precocious puberty  Hormones (Athens). 2015; 14 :65-71,

44-Poyrazoğlu Ş, Akçay T, Arslanoğlu İ, Atabek ME, Atay Z, Berberoğlu M, Bereket  A, Bideci A, Bircan İ, Böber E, Can Ş, Cesur Y, Darcan Ş, Demir K, Dündar B, Ersoy B, Esen İ, Güven A, Kara C, Keskin M, Kurtoğlu S, Memioğlu N, Özbek MN, Özgen T, Sarı E, Şıklar Z, Şimşek E, Turan S, Yeşilkaya E, Yüksel B, Darendeliler F. Current Practice in Diagnosis and Treatment of Growth Hormone Deficiency in Childhood: A Survey from Turkey. J Clin Res Pediatr Endocrinol. 2015;7:37-44

45-Guran T, Buonocore F, Saka N, Nuri Ozbek M, Aycan Z, Bereket A, Bas F, Darcan  S, Bideci A, Guven A, Demir K, Akinci A, Buyukinan M, Kucukemre Aydin B, Turan S, Yilmaz Agladioglu S, Atay Z, Yavas Abali Z, Tarim O, Catli G, Yuksel B, Akcay T,  Yildiz M, Ozen S, Doger E, Demirbilek H, Ucar A, Isik E, Ozhan B, Bolu S, Tolga Ozgen I, Suntharalingham J, Achermann JC. Rare causes of primary adrenal insufficiency: Genetic and clinical characterization of a large nationwide cohort. J Clin Endocrinol Metab. 2015; 101:284-92. doi: 10.1210/jc.2015-3250.

46-Cebeci AN, Guven A, Kuru IL. Perinephritic adipose tissue thickness in relation to blood pressure, plasma apaelin and C-reactive protein levels in obese adolescents. Minerva Endocrinol 2016;41: 166-174

47-Dursun F, Güven A, Yıldız M. Assessment of Anti-Müllerian Hormone Level in Management of Adolescents with Polycystic Ovary Syndrome. J Clin Res Pediatr Endocrinol. 2016;8:55-60,

48-Güven A, Cebeci AN, Ellard S , Flanagan SE. Clinical, genetic characteristics, management and long-term follow up of Turkish patients with congenital hyperinsulinism.. J Clin Res Pediatr Endocrinol. 2016;8:197-204

49-Tracy A Briggs; Gillian I Rice; Navid Adib, Lesley Ades; Stephane Barete; Kannan Baskar; Veronique Baudouin, Ayse N. Cebeci, Philippe Clapuyt; David Coman Lien De Somer; Yael Finezilber; Moshe Frydman; Ayla Guven; Sébastien Heritier; Daniela Karall; Muralidhar L Kulkarni; Pierre Lebon;  David Levitt, Martine Le Merrer; Agnes Linglart; John H Livingstone; Vincent Navarro; Ericka Okenfuss; Anne Puel; Nicole Revencu; Sabine Scholl-Bürgi;; Marina Vivarelli; Carine Wouters, Brigitte Bader-Meunier; Yanick J Crow. Spondyloenchondrodysplasia due to mutations in ACP5: A comprehensive survey. Journal of Clinical Immunology 2016;36:220-234,

50-Şıklar Z, Genens M, Poyrazoğlu Ş, Baş F, Darendeliler F, Bundak R, Aycan Z, Savaş Erdeve Ş, Çetinkaya S, Güven A, Abalı S, Atay Z, Turan S, Kara C, Can Yılmaz G, Akyürek N, Abacı A, Çelmeli G, Sarı E, Yeşilkaya E, Bolu S, Korkmaz HA, Şimşek E, Çatlı G, Büyükinan M, Çayır A, Evliyaoğlu O, İşgüven P, Özgen IT, Hatipoğlu N, Elhan AH, Berberoğlu M. The growth characteristics of patients with Noonan syndrome, and first 3 years results of GH treatment: A Nationwide multicenter study. J Clin Res Pediatr Endocrinol. 2016 2016;8:305-12

51-Güven A, Polat S. Testicular Adrenal Rest Tumor In Brothers With Novel Mutation In 3-Beta Hydroxysteroid Dehydrogenase -2 Gene.  J Clin Res Pediatr Endocrinol 2017; 9; 85-90 

52-Güven A. Seven Cases With Williams Beuren Syndrome: Endocrine Evaluation And Long Term Follow-Up. J Pediatr Endocrinol Metab. 2017; 30:159-165

53-Guven A, Roua Al-Rijjal, Huda Binessa, Durmuş Dogan, Yilmaz Kor, Minjing Zou, Namik Kaya, Anwar Al-Enazi, Suna Hancili, Omer Tarim, Essa Baitei, Walaa Kattan, Brian Meyer, Yufei Shi. Mutational Analysis of PHEX, FGF23 and CLCN5 in Patients with Hypophosphatemic Rickets. Clin Endocrinol (Oxf) 2017;87:103-11253-

54-Hancili S, Bonnefond A,Philippe J, Vaillant E,  De Graeve F, Sand O, Busiah K, Robert JJ, Polak M, Froguel P, Güven A,Vaxillaire M. A novel NEUROG3 mutation in neonatal diabetes associated with a neuro-intestinal syndrome. Pediatric Diabetes. 2018; 19: 381-387

55-Johnson MB, De Franco E, Allen HL, Al Senani A, Elbarbary N, Siklar Z, Berberoglu M, Imane Z, Haghighi A, Razavi Z, Ullah I, Alyaarubi S, Gardner D, Güven A, Ellard S, Hattersley AT, Flanagan SE. Erratum. Recessively Inherited LRBA Mutations Cause Autoimmunity Presenting as Neonatal Diabetes. Diabetes 2017;66:2316-2322. Diabetes. 2018 Jan 5. pii: db18er03b.

56-Erol N, Yıldız M, Güven A, Yıldırım A. Cardiac examination in children with Laron syndrome undergoing mecasermin therapy. J Pediatr Endocrinol Metab. 2018 Jun 27;31(6):675-679.

57-Kılınç S, Yücel-Yılmaz D, Ardagil A, Apaydın S, Valverde D, Özgül RK, Güven A. Five novel ALMS1 gene mutations in six patients with Alström syndrome. J Pediatr Endocrinol Metab. 2018 Jun 27;31(6):681-687.

58-Poyrazoğlu Ş, Bundak R, Yavaş Abalı Z, Önal H, Sarıkaya S, Akgün A, Baş S, Abalı S, Bereket A, Eren E, Tarım Ö, Güven A, Yıldız M, Karaman Aksakal D, Yüksel A, Seymen Karabulut G, Hatun Ş, Özgen T, Cesur Y, Azizoğlu M, Dilek E, Tütüncüler F, Papatya Çakır E, Özcabı B, Evliyaoğlu O, Karadeniz S, Dursun F, Bolu S, Arslanoğlu İ, Yeşiltepe Mutlu G, Kırmızıbekmez H, İşgüven P, Üstyol A, Adal E, Uçar A, Cebeci N, Bezen D, Binay Ç, Semiz S, Korkmaz HA, Memioğlu N, Sagsak E, Peltek HN, Yıldız M, Akçay T, Turan S, Güran T, Atay Z, Akcan N, Çizmecioğlu F, Ercan O, Dağdeviren A, Baş F, İşsever H, Darendeliler F. Incidence of Type 1 Diabetes in Children Aged Below 18 Years During 2013-2015 in Northwest Turkey. J  Clin Res Pediatr Endocrinol. 2018 Nov 29;10(4):336-342.

59-Abacı A, Çatlı G, Kırbıyık Ö, Şahin NM, Abalı ZY, Ünal E, Şıklar Z, Mengen E,  Özen S, Güran T, Kara C, Yıldız M, Eren E, Nalbantoğlu Ö, Güven A, Çayır A, Akbaş ED, Kor Y, Çürek Y, Aycan Z, Baş F, Darcan Ş, Berberoğlu M. Genotype-phenotype correlation, gonadal malignancy risk, gender preference, and testosterone/dihydrotestosterone ratio in steroid 5-alpha-reductase type 2 deficiency: a multicenter study from Turkey.J Endocrinol Invest. 2019 Apr;42(4):453-470

60-Akıncı A, Turkkahraman D, Tekedereli I, Özer L, Evren B, Sahin İ, Kalkan T, Çürek Y, Çamtosun E, Doğer E, Bideci A, Güven A, Eren E, Sangün Ö, Çayır A, Bilir P, Törel Ergür A, Ercan O. Novel Mutations in Obesity-Related Genes in Turkish Children with Non-Syndromic Early Onset Severe Obesity: A Multicentre Study. J Clin Res Pediatr Endocrinol. 2019;11:341-349

61-Kiykim A,Dursun E, Ogulur I, Charbonnier LM, Nain E,Cekic S, Dogruel D, Karaca NE, Cogurlu MT, Bilir OA, Cansever M, Kapaklı H, Baser D, Kasap N, Kutlug S, Altintas DU, Al‐Shaibi A, Agrebi N, Kara M, Guven A, Somer A, Aydogmus C, Ayaz NA, Metin A, Aydogan M, Uncuoglu A, Patiroglu T, Yildiran A, Guner SN,Keles S, Reisli I, Aksu G, Kutukculer N, Kilic SS, Yilmaz M, Karakoc-Aydiner E, Lo B, Ozen A, Chatila TA, MD, Baris S. Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency. J Allergy Clin Immunol Pract. 2019;7:2790-2800

62-Pofi R, Prete A, Thornton-Jones V, Bryce J, Ali SR, Faisal Ahmed S, Balsamo A, Baronio F, Cannuccia A, Guven A, Guran T, Darendeliler F, Higham C, Bonfig W, de  Vries L, Bachega TASS, Miranda MC, Mendonca BB, Iotova V, Korbonits M, Krone NP,  Krone R, Lenzi A, Arlt W, Ross RJ, Isidori AM, Tomlinson JW. Plasma Renin Measurements are Unrelated to Mineralocorticoid Replacement Dose in Patients With Primary Adrenal Insufficiency. J Clin Endocrinol Metab. 2020;105(1):314-326

63-Guran T, Kara C, Yildiz M, Bitkin EC, Haklar G, Lin JC, Keskin M, Barnard L, Anik A, Catli G, Guven A, Kirel B, Tutunculer F, Onal H, Turan S, Akcay T, Atay Z, Yilmaz GC, Mamadova J, Akbarzade A, Sirikci O, Storbeck KH, Baris T, Chung BC, Bereket A. Revisiting Classical 3β-hydroxysteroid Dehydrogenase 2 Deficiency: Lessons from 31 Pediatric Cases. J Clin Endocrinol Metab. 2020;105(3):e1718-e1728.

64-Güven A. Different Potent Glucocorticoids, Different Routes of Exposure but The Same Result: Iatrogenic Cushing’s syndrome and Adrenal Insufficiency. J Clin Res Pediatr Endocrinol 2020;12:383-392

65-Güven A, Konrad M, Schlingmann KP. Idiopathic infantile hypercalcemia: Mutations in SLC34A1 and CYP24A1 in two siblings and fathers. JPEM 2020; 33:1353-1358

66-Zou M, Guven A, BinEssa HA, Al-Rijjal RA, Meyer BF, Alzahrani AS and Shi Y (2020) Molecular Analysis of CYP27B1 Mutations in Vitamin D-Dependent Rickets Type 1A:c.590G > A (p.G197D) Missense Mutation Causes a RNA Splicing Error. Front. Genet. 11:607517.

67-Ali SR, Bryce J, Haghpanahan H, Lewsey JD, Tan LE, Atapattu N, Birkebaek NH, Blankenstein O, Neumann U, Balsamo A, Ortolano R, Bonfig W, Claahsen-van der Grinten HL, Cools M, Costa EC, Darendeliler F, Poyrazoglu S, Elsedfy H, Finken MJJ, Fluck CE, Gevers E, Korbonits M, Guaragna-Filho G, Guran T, Guven A, Hannema SE, Higham C, Hughes IA, Tadokoro-Cuccaro R, Thankamony A, Iotova V, Krone NP, Krone R, Lichiardopol C, Luczay A, Mendonca BB, Bachega TASS, Miranda MC, Milenkovic T, Mohnike K, Nordenstrom A, Einaudi S, van der Kamp H, Vieites A, de Vries L, Ross RJM, Ahmed SF. Real World Estimates Of Adrenal Insufficiency Related Adverse Events In Children With Congenital Adrenal Hyperplasia. 2021;106(1):e192-e203

68-Bacila I, Freeman N, Daniel E, Sandrk M, Bryce J, Ali SR, Yavas Abali Z, Atapattu N, Bachega TA, Balsamo A, Birkebæk N, Blankenstein O, Bonfig W, Cools M, Costa EC, Darendeliler F, Einaudi S, Elsedfy HH, Finken M, Gevers E, Claahsen-van der Grinten HL, Guran T, Güven A, Hannema SE, Higham CE, Iotova V, van der Kamp HJ, Korbonits M, Krone RE, Lichiardopol C, Luczay A, Mendonca BB, Milenkovic T, Miranda MC, Mohnike K, Neumann U, Ortolano R, Poyrazoglu S, Thankamony A, Tomlinson JW, Vieites A, de Vries L, Ahmed SF, Ross RJ, Krone NP.International practice of corticosteroid replacement therapy in congenital adrenal hyperplasia: data from the I-CAH registry. Eur J Endocrinol. 2021 Apr;184(4):553-563.

69-Hebenstreit D, Ahmed SF, Krone N, Krall C, Bryce J, Alvi S, Ortolano R, Lima M, Birkebaek N, Bonfig W, Claahsen van der Grinten H, Costa EC, Poyrazoglu S, de Vries L, Flück CE, Guran T, Bugrul F, Güven A, Iotova V, Koehler B, Schröder JT, Konrad D, Gevers E, Krone R, Milenkovic T, Vieites A, Ross R, Tadokoro Cuccaro R, Hughes I, Acerini C, Springer A.Surgical Practice In Girls With Congenital Adrenal Hyperplasia – An International Registry  Study. Sex Dev. 2021;15(4):229-235.

70-Lucas-Herald AK, Bryce J, Kyriakou A, Ljubicic ML, Arlt W, Audi L, Balsamo A, Baronio F, Bertelloni S, Bettendorf M, Brooke A, Claahsen van der Grinten HL, Davies JH, Hermann G, de Vries L, Hughes IA, Tadokoro-Cuccaro R, Darendeliler F, Poyrazoglu S, Ellaithi M, Evliyaoglu O, Fica S, Nedelea L, Gawlik A, Globa E, Zelinska N, Guran T, Güven A, Hannema SE, Hiort O, Holterhus PM, Iotova V, Mladenov V, Jain V, Sharma R, Jennane F, Johnston C, Guerra Junior G, Konrad D, Gaisl O, Krone N, Krone R, Lachlan K, Li D, Lichiardopol C, Lisa L, Markosyan R, Mazen I, Mohnike K, Niedziela M, Nordenstrom A, Rey R, Skaeil M, Tack LJW, Tomlinson J, Weintrob N, Cools M, Ahmed SF. Gonadectomy in conditions affecting sex development: a registry-based cohort study. Eur J Endocrinol. 2021;184(6):791-801.

71-Neumann U, van der Linde A, Krone RE, Krone NP, Güven A, Güran T, Elsedfy H, Poyrazoglu S, Darendeliler F, Bachega TASS, Balsamo A, Hannema SE, Birkebaek N, Vieites A, Thankamony A, Cools M, Milenkovic T, Bonfig W, Costa EC, Atapattu N, de Vries L, Guaragna-Filho G, Korbonits M, Mohnike K, Bryce J, Ahmed SF, Voet B, Blankenstein O, Claahsen-van der Grinten HL.Treatment of congenital adrenal hyperplasia in children aged 0-3 years: a retrospective multicenter analysis of salt supplementation, glucocorticoid and mineralocorticoid medication, growth and blood pressure. Eur J Endocrinol 2022 ;186(5):587-596.

72-Demirtas A, Girgin BA, Güven A, Kırmızıbekmez H. Psychometric Properties of the Turkish Version of the Diabetes Strengths and Resilience Measure for Adolescents with Type 1 Diabetes.  J Clin Res Pediatric Endocrinol 2022; 14(3):324-333.

73-Eylem Kiral, Birgul Kirel, Merve Havan, Mehmet Keskin, Murat Karaoglan, Ahmet Yıldırım, Murat Kangin, Mehmet Nur Talay, Tuba Urun, Umit Altug, Selman Kesici, Erennur Tufan, Ebru Kacmaz, Gurkan Bozan, Ebru Azapagasi, Mutlu Uysal Yazici, Zeynel Abidin Oztürk, Osman Yesilbas, Gulay Karaguzel, Ulkem Barlas, Muhterem Duyu, Merve Boyraz, Esra Sevketoglu, Nihal Akçay, Suna Hancili, Ayla Güven, Oğuz Dursun, Nazan Ulgen Tekerek, Gokçen Ozcifci, Pınar Yazici, Eda Turanli, Tanıl Kendirli, Fevzi Kahveci, Ayse Filiz Yetimakman, Agop Çıtak, Guntulu Şık, Ibrahim Bingol, Fatih Aygun, Cansu Durak, Resul Yılmaz, Fuat Bugrul, Yusuf Sari, Hakan Tekguç, Hatice Albayrak, Nazik Yener, Hasan Agin, Ekin Sodan, Dincer Yildizdas, Semine Ozdemir Dile, Nilufer Yalindag, Feyza Incekoy Girgin, Nuri Alacakir, Filiz Tutunculer, Mehmet Ozgur Arslanaoglu, Muzaffer Bilgin, Can Aydin, Enver Simsek, Ener Cagri Dinleyici. Increased severe cases and new-onset type 1 diabetes among children presenting with diabetic ketoacidosis during first year of COVID-19 pandemic in Turkey. Frontiers in Pediatrics 2022;10: 926013.

74-Lawrence N, Bacila I, Dawson J, Bryce J, Ali SR, van den Akker EL, Bachega TASS, Baronio F, Birkebaek NH, Bonfig W, Claahsen van der Grinten H, Costa EC, de Vries L, Elsedfy H, Güven A, Hannema S, Iotova V, van der Kamp HJ, León MC, Lichiardopol CR, Milenkovic T, Neumann U, Nordenström A, Poyrazoğlu Ş, Probst-Scheidegger U, De Sanctis L, Tadokoro-Cuccaro R, Thankamony A, Vieites A, Yavaş Z, Faisal Ahmed S, Krone N. Analyses  of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry. Clin Endocrinol (Oxf). 2022;97(5):551-561.

75-Erdogan F, Güven A. Is there a secular trend regarding puberty in children with down syndrome? Front Endocrinol (Lausanne). 2022 Nov 15;13:1001985. doi: 10.3389/fendo.2022.1001985. eCollection 2022.

76-Cioana M, Deng J, Nadarajah A, Hou M, Qiu Y, Chen SSJ, Rivas A, Banfield L, Toor PP, Zhou F, Guven A, Alfaraidi H, Alotaibi A, Thabane L, Samaan MC. The Prevalence of Obesity Among Children with Type 2 Diabetes: A systematic review and Meta-analysis. JAMA Netw Open. 2022 Dec 1;5(12):e2247186.

77-Schröder MAM, Neacşu M, Adriaansen BPH, Sweep FCGJ, Ahmed SF, Ali SR, Bachega TASS, Baronio F, Birkebæk NH, de Bruin C, Bonfig W, Bryce J, Clemente M, Cools M, Elsedfy H, Globa E, Guran T, Güven A, Amr NH, Janus D, Taube NL, Markosyan R, Miranda M, Poyrazoğlu Ş, Rees A, Salerno M, Stancampiano MR, Vieites A, de Vries L, Yavas Abali Z, Span PN, Claahsen-van der Grinten HL. Hormonal control during infancy and testicular adrenal rest tumor development in CAH males – a retrospective multi-center cohort study.  Eur J Endocrinol. 2023 Oct 17;189(4):460-468. doi: 10.1093/ejendo/lvad143.

78- Tseretopoulou X, Ali SR, Bryce J, Amin N, Atapattu N, Bachega TASS, Baronio F, Ortolano R, Birkebaek NH, Bonfig W, Cools M, Davies JH, Thomas T, de Vries L, Elsedfy H, Amr NH, Flueck CE, Globa E, Guran T, Yavas-Abali Z, Guven A, Hannema SE, Iotova V, Konrad D, Lenherr-Taube N, Krone NP, Leka-Emiri S, Vlachopapadopoulou E, Lichiardopol C, Marginean O, Markosyan R, Neumann U, Niedziela M, Banaszak-Ziemska M, Phan-Hug F, Poyrazoglu S, Probst-Scheidegger U, Randell T, Russo G, Salerno M, Seneviratne S, Shnorhavorian M, Thankamony A, Tadokoro-Curraro R, van den Akker E, van Eck J, Vieites A, Wasniewska M, Ahmed SF. Temporal Trends in Acute Adrenal Insufficiency Events in Children With Congenital Adrenal Hyperplasia During 2019-2022. J Endocr Soc. 2024 Aug 20;8(10):bvae145.

A2. SCI ve SCI-E DIŞINDAKİ DERGİLERDE YAYINLANAN MAKALELER

1-Güven A. Baskin D. Lymphomatoid Granulomatosis at Young Age. SIIC Salud. 2003; 24 September. [http://www.siicsalud.com/main/siicestr.htm]

2-Güven A, Aydın M. Beş yaşından önce diyabet tanısı alan çocuklarda etiopatogenezde rol alan faktörler. Çocuk Sağlığı ve Hastalıkları Dergisi 2005; 48:295-300. 

3-Güven A, Koçak Ş, Aydın M, Ökten G, Oğur G. X izo kromozomuna sahip Turner Sendromlu bir olgu sunumu. OMU Tıp Dergisi 2006; 23:29-32. 

4-İşgüven, P, Yıldız M, Ergüven M, Malçok M, Güven A. Bez Dermatiti Nedeniyle Kullanılan Topikal Steroide Bağlı Cushing Sendromu: Olgu Sunumu. Güncel Pediatri, 2007;5: 35-37.

5-Güven A, Ozgen T, Güngör O, Aydın M, Baysal K. Association Between the Corrected QT Interval and Carotid Artery Intima-Media Thickness in Obese Children. J Clin Res Pediatr Endocrinol. 2010;2:21-27.

6-Güven A, Cebeci AN. 3M Syndrome:  a report of four cases in two families. J Clin Res Pediatr Endocrinol 2011;3:154-159.

7-Erkan Mesci, Afitap İçağasıoğlu, Yasemin Yumuşakhuylu, Ayla Güven, İrem Bıçakçı. Obez Çocuklarda Muskuloskeletal Ağrı/Muskuloskeletal pain in Obese Children.J Clin Anal Med 2015;6(suppl 4): 514-8-

8-Cebeci AN, Guven A, Mutus M, Zemheri E. ACTH-Independent Cushing Syndrome in an Adolescent Girl due to Micronodular Adrenal Hyperplasia. J Pediatri Endocrinol 2016;1004.

9—İ Öğülür, A Kıykım, E Nain, A Somer, A Güven, S Barış, A Özen, E Karakoç. Protein Expression in the Diagnosis of LRBA Deficiency by Flow Cytometer. Asthma Allergy Immunol 2017;15:1-9

10-Özsoy Koyun I, Ardagil Akçakaya A, Simsek B, Güven A, Koyun E. Topographic and refractive findings in osteogenesis imperfecta. Medeniyet Medical Journal. 2018;33: 291-295.

11-Celep G, Varol K, Erdoğan Y,  Uyar R, Kahraman BA, Güven A. Epididimoorşitle Seyreden Bir Suçiçeği Olgusu, Bir Tesadüften Fazlası mı? J Pediatr Inf 2019;13:105-108

12-Ozcabi B, Demirhan S, Akyol M, Ozturkmen Akay H, Güven A. Lipid accumulation Product is a Predictor of Nonalcoholic Fatty Liver Disease in Childhood Obesity. Korean J Pediatr 2019; 62: 450-455.

13-Kılınc S, Yildiz M, Guven A. Analysis of Metabolic Features and Cardiovascular Risk Factors in a Group of Patients with Turner Syndrome. J Pediatri Endocrinol. 2020; 5(1): 1031.

14-Kilinc S, Yildiz M, Guven A. Associated clinical Abnormalities Among Patients with Turner Syndrome. North Clin Istanb. 2020;7:226-230.

15-Özcabı B, Vatansever M, Güven A. Hypogonadism: is-it always hypogonadotropic in an adolescent with a cleft palate? A surprising case of Klinefelter syndrome. Cleft Palate Craniofac J 2021; 58(6):787-790. 

16-Güven A, Cebeci AN. A Rare Endocrine Manifestation of Down syndrome: Central Precocious Puberty: Three Cases Report. EJMCR 2020; 4: 404-407. 

17-Çelebi F, Ozcabı B, Güven A. The Relationship Between Obesity, Depressive Symptoms and Sleep Duration in Children and Adolescents. Acta Medica Alanya 2021: 5 (1): 42-47

Kitap Bölümleri:

1-Güven A. Plasentanın endokrin fonksiyonları. In: Kurdoğlu S (ed). Yenidoğan Dönemi Endokrin Hastalıkları, 2011,Nobel Matbaacılık,İstanbul, 7-20

2-Güven A. Hipofiz Fonksiyon Testleri, Endokrin testler, Dinamik Testler. In :Cinaz P,Darendeliler F,Akıncı A,ÖzkanB,Dündar B,Abacı A,Akçay T (eds): Çocuk Endokrinoloji,2.Baskı,2013,771-783 

3-Güven A. Cushing’s Sendromu ve Perioperatif Yönetim. In: Kurdoğlu S (ed). Çocuklarda Acil Endokrin Hastalıklar, Nobel Tıp Kitabevi, İstanbul, 2013:463-469

4-Ayla Güven. Polikistik Over Sendromunda Tedavi. In: Haspolat YK, Gül T,Yolbaş I, Aktar F (eds). Adolesan Jinekolojisi, Cinius Yayınları, İstanbul,2016 : 209-218.

5-Ayla Güven. Uzun Boy. In: Darendeliler F, Aycan Z, Kara C, Özen S, Eren E (eds). Çocuk Endokrinolojisi ve Diyabet. Cilt 1, 1.Baskı, İstanbul Medikal Sağlık ve Yayıncılık Siz Tic Ltd Şti, 23 Nisan 2021: 290-316

6-Ayla Güven. Aşırı Büyüme. In: Darendeliler F, Aycan Z, Kara C, Özen S, Eren E (eds). Çocuk Endokrinolojisi ve Diyabet. Cilt 1, 1.Baskı,İstanbul Medikal Sağlık ve Yayıncılık Siz Tic Ltd Şti 23 Nisan 2021: 317-341

7-Güven A. Mitokondriyal hastalıklarda endokrinopatiler. Ünal uzun Ö, editör. Çocukluk Çağında Mitokondriyal Hastalıklar. 1. Baskı. Ankara: Türkiye klinikleri; 2022. p.58-67. 

8-Ayla Güven.  Uzun boy ve uzun boyla seyreden aşırı büyüme sendromları. In: Darendeliler F, Aycan Z, Kara C, Özen S, Eren E (eds). Temel Çocuk Endokrinolojisi ve Diyabet. İstanbul Medikal Sağlık ve Yayıncılık Hiz Tic Ltd Şti, 2023. 116-135. ISBN: 978-625-8103-24-3